Publications

• Cross H, Peng J, …, Robinson GA. Type I interferon endotypes drive divergent clinical trajectories in childhood-onset SLE uncovered through a novel systems immunology approach. Ann Rheum Dis 2026. doi.org/10.1016/j.ard.2025.12.011 Joint first authors Cross and Peng
• Robinson GA, et al. Insights into the pathogenesis of childhood-onset SLE in the past decade. Nat Rev Rheumatol 2025. doi.org/10.1038/s41584-025-01321-x
• Ciurtin C, Peng J, Gao Y, Niwa M, Ardoin S, Schanberg L, Lewandowski L, Jury EC, Robinson GA. Investigation of the performance of validated cardiovascular risk scores in a global (UK/US) cohort of young people with childhood-onset systemic lupus erythematosus. Lupus Sci Med 2024. doi.org/10.1136/lupus-2024-001194
• Peng J, …, Robinson GA, et al. Atherosclerosis progression in the APPLE trial can be predicted in young people with juvenile-onset systemic lupus erythematosus using a novel lipid metabolomic signature. Arthritis Rheumatol 2023. doi.org/10.1002/art.42722 Co-senior author. ACR top publications 2024
• Jury EC, …, Robinson GA. Systemic lupus erythematosus patients have unique changes in serum metabolic profiles across age associated with cardiometabolic risk. Rheumatology 2023. doi.org/10.1093/rheumatology/kead646
• Robinson GA, et al. Investigating sex differences in T regulatory cells from cisgender and transgender healthy individuals and patients with autoimmune inflammatory disease: a cross-sectional study. Lancet Rheumatol 2022. doi.org/10.1016/S2665-9913(22)00198-9 Journal cover
• Ciurtin C, Pineda-Torra I, Jury EC, Robinson GA. CD8+ T-cells in juvenile-onset SLE: from pathogenesis to comorbidities. Front Med 2022. doi.org/10.3389/fmed.2022.904435
• Robinson GA, et al. Sex differences in lipid metabolism: implications for systemic lupus erythematosus and cardiovascular disease risk. Front Med 2022. doi.org/10.3389/fmed.2022.914016
• Robinson GA, et al. The role of immunometabolism in the pathogenesis of systemic lupus erythematosus. Front Immunol 2022. doi.org/10.3389/fimmu.2021.806560
• Robinson GA, et al. Lipid metabolism in autoimmune rheumatic disease: implications for modern and conventional therapies. J Clin Invest 2022. doi.org/10.1172/JCI148552
• Robinson GA, et al. Metabolomics defines complex patterns of dyslipidaemia in juvenile-SLE patients associated with inflammation and potential cardiovascular disease risk. Metabolites 2021. doi.org/10.3390/metabo12010003
• Robinson GA, et al. Sex hormones drive changes in lipoprotein metabolism. iScience 2021. doi.org/10.1016/j.isci.2021.103257
• Robinson GA, et al. Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE. EBioMedicine 2021. doi.org/10.1016/j.ebiom.2021.103243
• Robinson GA, et al. Disease-associated and patient-specific immune cell signatures in juvenile-onset systemic lupus erythematosus: patient stratification using a machine-learning approach. Lancet Rheumatol 2020. doi.org/10.1016/S2665-9913(20)30168-5 Journal cover
• Robinson GA, et al. Diet and lupus: what do the patients think?. Lupus 2019. doi.org/10.1177/0961203319845473
• Robinson GA, et al. Transcriptional regulation of T-cell lipid metabolism: implications for plasma membrane lipid rafts and T-cell function. Front Immunol 2017. doi.org/10.3389/fimmu.2017.01636

Studies led by collaborating groups, to which our group contributed.

• Knippenberg A, Robinson GA, et al. Plant-based dietary changes may improve symptoms in patients with systemic lupus erythematosus. Lupus 2022. doi.org/10.1177/09612033211063795
• Oppong AE, Coelewij L, Hutchinson M, Carpenter B, Robinson GA, et al. Simple hyperinflammation scores predict mortality in hospitalized patients with COVID-19 and offer a personalized medicine approach to dexamethasone intervention. Int J Infect Dis 2025. doi.org/10.1016/j.ijid.2025.108119
• Woodridge L, Tektonidou MG, Robinson GA, et al. Subclinical atherosclerosis risk can be predicted in female patients with systemic lupus erythematosus using metabolomic signatures: an observational study. J Am Heart Assoc 2025. doi.org/10.1161/JAHA.124.036507
• Radziszewska A, …, Robinson GA, et al. Type I interferon and mitochondrial dysfunction are associated with dysregulated cytotoxic CD8+ T cell responses in juvenile systemic lupus erythematosus. Clin Exp Immunol 2025. doi.org/10.1093/cei/uxae127
• Peckham H, …, Robinson GA, et al. Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes. J Exp Med 2025. doi.org/10.1084/jem.20241253
• Ciurtin C, Robinson GA, et al. Cardiovascular risk in young people with childhood onset systemic lupus erythematosus. Lancet Rheumatol 2024. doi.org/10.1016/S2665-9913(24)00085-7
• Rodríguez-Carrio J, …, Robinson GA, et al. Humoral responses against HDL are linked to lipoprotein traits, atherosclerosis, inflammation and pathogenic pathways during early arthritis stages. Rheumatology 2023. doi.org/10.1093/rheumatology/kead009
• Allalou A, Peng J, Robinson GA, et al. Impact of puberty, sex determinants and chronic inflammation on cardiovascular risk in young people. Front Cardiovasc Med 2023. doi.org/10.3389/fcvm.2023.1191119
• Waddington KE, Robinson GA, et al. LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function. PNAS 2021. doi.org/10.1073/pnas.2017394118
• Coelewij L, Waddington KE, Robinson GA, et al. Serum metabolomic signatures can predict subclinical atherosclerosis in patients with systemic lupus erythematosus. Arterioscler Thromb Vasc Biol 2021. doi.org/10.1161/ATVBAHA.120.315321
• Martin-Gutierrez L, …, Robinson GA, et al. Stratification of patients with Sjögren's syndrome and patients with systemic lupus erythematosus according to two shared immune cell signatures, with potential therapeutic implications. Arthritis Rheumatol 2021. doi.org/10.1002/art.41708
• Manson JJ, …, Robinson GA, et al. COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study. Lancet Rheumatol 2020. doi.org/10.1016/S2665-9913(20)30275-7

• Serum proteomics (Olink) data of childhood-onset SLE patients and healthy controls. Mendeley Data 2026. doi.org/10.17632/fwsw46ktyp.1
• Bulk transcriptomics of peripheral blood mononuclear cells of childhood-onset SLE patients and healthy controls. Mendeley Data 2026. doi.org/10.17632/tkpnnc23k8.1
• Metabolomics data across age on serum from SLE patients and healthy controls. Mendeley Data 2023. doi.org/10.17632/pngxy9sg9c.1
• RNA-seq of human Tregs from healthy cisgender and transgender individuals and patients with JSLE. ArrayExpress 2022. Accession E-MTAB-11919
• Metabolomics data on serum from cisgender and transgender individuals. Mendeley Data 2021. doi.org/10.17632/3nxny453ch.1
• RNA-seq of human CD4+ and CD8+ T cells from patients with JSLE. ArrayExpress 2020. Accession E-MTAB-9329
• JSLE and healthy control immune phenotype. Mendeley Data 2020. doi.org/10.17632/mcsypbk6nz.2
• JSLE and healthy control metabolomics. Mendeley Data 2020. doi.org/10.17632/8b7v9rdjwt.2